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Troponin C (AA 1-160) Protéine

Protéine Recombinant exprimée dans Escherichia coli (E. coli).
N° du produit ABIN935041

Aperçu rapide pour Troponin C (AA 1-160) Protéine (ABIN935041)

Antigène

Troponin C

Type de proteíne

Recombinant

Origine

  • 1
  • 1
  • 1
Humain

Source

  • 2
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Pureté

> 95 % pure
  • Attributs du protein

    AA 1-160

    Séquence

    MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ

    Attributs du produit

    Purified recombinant Human Troponin C protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
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  • Indications d'application

    Troponin C protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0 mM DTT, 100 mM NaCl, and 10 % glycerol.

    Agent conservateur

    Dithiothreitol (DTT)

    Précaution d'utilisation

    This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    RT/-20 °C

    Stockage commentaire

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Antigène

    Troponin C

    Sujet

    Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I(Tn-1), Troponin T(Tn-T) and Troponin C(Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Recombinant human Troponin C was expressed in E. coli and purified by using conventional chromatography.
    Alternative Names: Troponin C protein, , Fast skeletal muscle troponin C protein, skeletal muscle protein, Troponin C protein, TNNC2 protein, Troponin C protein, Troponin C type 1 (slow) protein, skeletal muscle TNNC1 protein, Cardiac troponin C protein, Skeletal troponin C protein, slow skeletal and cardiac muscles protein, TNNC protein, Troponin C1 slow protein, Troponin C type 2 (fast) protein

    Poids moléculaire

    18.1 kDa (160 AA)
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